Superimmunity

Under these conditions, inoculations with the virus cause a reaction fever without any internal symptoms of the disease and in this way generally, after 3 inoculations, superimmunity is assured against natural infection which lasts during the whole dairy period for milch cows.

The goal of cloning superimmunity to the limited number of phages that attack some S. cremoris strains, in particular, is attractive. A prerequisite, however, is a concerted study of the biochemistry and molecular biology of phage repressor systems in the lactic streptococci.

Our results are consistent with those obtained by other groups screening camelid-derived libraries, where an impressive diversity in the Nb nucleotide sequence, specificity and neutralizing capacity was found, especially after successive immunizations to promote the development of superimmunity.